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A swine model of acute thrombocytopenia with prolonged bleeding time produced by busulfan
Animal models of thrombocytopenia are indispensable for evaluating the in vivo efficacy of hemostatic agents, cryopreserved platelets, and artificial platelets, but no large animal models are available. In this study, we generated a swine model of acute thrombocytopenia with prolonged bleeding times...
Autores principales: | Abe, Tomoyuki, Kono, Shota, Ohnuki, Takahiro, Hishikawa, Shuji, Kunita, Satoshi, Hanazono, Yutaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Association for Laboratory Animal Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111837/ https://www.ncbi.nlm.nih.gov/pubmed/27333841 http://dx.doi.org/10.1538/expanim.16-0022 |
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