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An HBV-tolerant immunocompetent model that effectively simulates chronic hepatitis B virus infection in mice

Hepatitis B virus (HBV) is the leading cause of liver disease and hepatic carcinoma (HCC). Approximately 350 million people worldwide are infected with HBV and at risk of chronicity. An efficient HBV-tolerant murine model that mimics HBV infection in humans is desirable for HBV-related research. In...

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Detalles Bibliográficos
Autores principales: Yuan, Lunzhi, Wang, Tengyun, Zhang, Yali, Liu, Xuan, Zhang, Tianying, Li, Xiaoling, Liu, Pingguo, Wu, Kun, Shih, James Wai Kuo, Yuan, Quan, Cheng, Tong, Xia, Ningshao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111840/
https://www.ncbi.nlm.nih.gov/pubmed/27264142
http://dx.doi.org/10.1538/expanim.16-0013