Physiological and pharmacokinetic effects of multilevel caging on Sprague Dawley rats under ketamine-xylazine anesthesia

While the cage refinement is a necessary step towards improving the welfare of research rats, increasing the complexity and surface area of the living space of an animal may have physiological impacts that need to be taken into consideration. In this study, ketamine (80 mg/kg) and xylazine (10 mg/kg...

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Detalles Bibliográficos
Autores principales: Dodelet-Devillers, Aurore, Zullian, Chiara, Beaudry, Francis, Gourdon, Jim, Chevrette, Julie, Hélie, Pierre, Vachon, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2016
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111841/
https://www.ncbi.nlm.nih.gov/pubmed/27263962
http://dx.doi.org/10.1538/expanim.16-0026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111841/
https://www.ncbi.nlm.nih.gov/pubmed/27263962
http://dx.doi.org/10.1538/expanim.16-0026

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