DNA methylation directs genomic localization of Mbd2 and Mbd3 in embryonic stem cells

Cytosine methylation is an epigenetic and regulatory mark that functions in part through recruitment of chromatin remodeling complexes containing methyl-CpG binding domain (MBD) proteins. Two MBD proteins, Mbd2 and Mbd3, were previously shown to bind methylated or hydroxymethylated DNA, respectively...

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Detalles Bibliográficos
Autores principales: Hainer, Sarah J, McCannell, Kurtis N, Yu, Jun, Ee, Ly-Sha, Zhu, Lihua J, Rando, Oliver J, Fazzio, Thomas G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111885/
https://www.ncbi.nlm.nih.gov/pubmed/27849519
http://dx.doi.org/10.7554/eLife.21964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111885/
https://www.ncbi.nlm.nih.gov/pubmed/27849519
http://dx.doi.org/10.7554/eLife.21964

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