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DNA methylation directs genomic localization of Mbd2 and Mbd3 in embryonic stem cells
Cytosine methylation is an epigenetic and regulatory mark that functions in part through recruitment of chromatin remodeling complexes containing methyl-CpG binding domain (MBD) proteins. Two MBD proteins, Mbd2 and Mbd3, were previously shown to bind methylated or hydroxymethylated DNA, respectively...
Autores principales: | Hainer, Sarah J, McCannell, Kurtis N, Yu, Jun, Ee, Ly-Sha, Zhu, Lihua J, Rando, Oliver J, Fazzio, Thomas G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111885/ https://www.ncbi.nlm.nih.gov/pubmed/27849519 http://dx.doi.org/10.7554/eLife.21964 |
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