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Charge neutralization as the major factor for the assembly of nucleocapsid-like particles from C-terminal truncated hepatitis C virus core protein

BACKGROUND: Hepatitis C virus (HCV) core protein, in addition to its structural role to form the nucleocapsid assembly, plays a critical role in HCV pathogenesis by interfering in several cellular processes, including microRNA and mRNA homeostasis. The C-terminal truncated HCV core protein (C124) is...

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Detalles Bibliográficos
Autores principales: de Souza, Theo Luiz Ferraz, de Lima, Sheila Maria Barbosa, Braga, Vanessa L. de Azevedo, Peabody, David S., Ferreira, Davis Fernandes, Bianconi, M. Lucia, Gomes, Andre Marco de Oliveira, Silva, Jerson Lima, de Oliveira, Andréa Cheble
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111903/
https://www.ncbi.nlm.nih.gov/pubmed/27867765
http://dx.doi.org/10.7717/peerj.2670