Microphthalmia-Associated Transcription Factor Suppresses Invasion by Reducing Intracellular GTP Pools

Melanoma progression is associated with increased invasion and, often, decreased levels of microphthalmia-associated transcription factor (MITF). Accordingly, downregulation of MITF induces invasion in melanoma cells, however little is known about the underlying mechanisms. Here, we report for the f...

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Detalles Bibliográficos
Autores principales: Bianchi-Smiraglia, Anna, Bagati, Archis, Fink, Emily E., Moparthy, Sudha, Wawrzyniak, Joseph A., Marvin, Elizabeth K., Battaglia, Sebastiano, Jowdy, Peter, Kolesnikova, Maria, Foley, Colleen E., Berman, Albert E., Kozlova, Nadezhda I., Lipchick, Brittany C., Paul-Rosner, Leslie M., Bshara, Wiam, Ackroy, Jeff, Shewach, Donna S., Nikiforov, Mikhail A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112150/
https://www.ncbi.nlm.nih.gov/pubmed/27181209
http://dx.doi.org/10.1038/onc.2016.178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112150/
https://www.ncbi.nlm.nih.gov/pubmed/27181209
http://dx.doi.org/10.1038/onc.2016.178

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