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Differentially Methylated DNA Regions in Monozygotic Twin Pairs Discordant for Rheumatoid Arthritis: An Epigenome-Wide Study

OBJECTIVES: In an explorative epigenome-wide association study (EWAS) to search for gene independent, differentially methylated DNA positions and regions (DMRs) associated with rheumatoid arthritis (RA) by studying monozygotic (MZ) twin pairs discordant for RA. METHODS: Genomic DNA was isolated from...

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Detalles Bibliográficos
Autores principales: Svendsen, Anders J., Gervin, Kristina, Lyle, Robert, Christiansen, Lene, Kyvik, Kirsten, Junker, Peter, Nielsen, Christian, Houen, Gunnar, Tan, Qihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112246/
https://www.ncbi.nlm.nih.gov/pubmed/27909437
http://dx.doi.org/10.3389/fimmu.2016.00510