The TLR4-Active Morphine Metabolite Morphine-3-Glucuronide Does Not Elicit Macrophage Classical Activation In Vitro

Macrophages are abundant in the tumor microenvironment where they adopt a pro-tumor phenotype following alternative polarization induced by paracrine factors from cancer and stromal cells. In contrast, classically activated macrophages have tumoricidal activities, such that the polarization of tumor...

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Detalles Bibliográficos
Autores principales: Khabbazi, Samira, Xie, Nan, Pu, Wenjun, Goumon, Yannick, Parat, Marie-Odile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112272/
https://www.ncbi.nlm.nih.gov/pubmed/27909407
http://dx.doi.org/10.3389/fphar.2016.00441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112272/
https://www.ncbi.nlm.nih.gov/pubmed/27909407
http://dx.doi.org/10.3389/fphar.2016.00441

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