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Maternal protein restriction during lactation modulated the expression and activity of rat offspring hepatic CYP1A1, CYP1A2, CYP2B1, CYP2B2, and CYP2E1 during development

Early nutrition plays a long-term role in the predisposition to chronic diseases and influences the metabolism of several drugs. This may happen through cytochromes P450 (CYPs) regulation, which are the main enzymes responsible for the metabolism of xenobiotics. Here, we analyzed the effects of mate...

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Detalles Bibliográficos
Autores principales: Da Costa, N. Meireles, Visoni, S.B.C., Dos Santos, I.L., Barja-Fidalgo, T.C., Ribeiro-Pinto, L.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112539/
https://www.ncbi.nlm.nih.gov/pubmed/27828666
http://dx.doi.org/10.1590/1414-431X20165238