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Intronless WNT10B-short variant underlies new recurrent allele-specific rearrangement in acute myeloid leukaemia

Defects in the control of Wnt signaling have emerged as a recurrent mechanism involved in cancer pathogenesis and acute myeloid leukaemia (AML), including the hematopoietic regeneration-associated WNT10B in AC133(bright) leukaemia cells, although the existence of a specific mechanism remains unprove...

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Detalles Bibliográficos
Autores principales: Lazzaroni, Francesca, Del Giacco, Luca, Biasci, Daniele, Turrini, Mauro, Prosperi, Laura, Brusamolino, Roberto, Cairoli, Roberto, Beghini, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112549/
https://www.ncbi.nlm.nih.gov/pubmed/27853307
http://dx.doi.org/10.1038/srep37201