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Intronless WNT10B-short variant underlies new recurrent allele-specific rearrangement in acute myeloid leukaemia
Defects in the control of Wnt signaling have emerged as a recurrent mechanism involved in cancer pathogenesis and acute myeloid leukaemia (AML), including the hematopoietic regeneration-associated WNT10B in AC133(bright) leukaemia cells, although the existence of a specific mechanism remains unprove...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112549/ https://www.ncbi.nlm.nih.gov/pubmed/27853307 http://dx.doi.org/10.1038/srep37201 |