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Characterizing Focused-Ultrasound Mediated Drug Delivery to the Heterogeneous Primate Brain In Vivo with Acoustic Monitoring

Focused ultrasound with microbubbles has been used to noninvasively and selectively deliver pharmacological agents across the blood-brain barrier (BBB) for treating brain diseases. Acoustic cavitation monitoring could serve as an on-line tool to assess and control the treatment. While it demonstrate...

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Detalles Bibliográficos
Autores principales: Wu, Shih-Ying, Sanchez, Carlos Sierra, Samiotaki, Gesthimani, Buch, Amanda, Ferrera, Vincent P., Konofagou, Elisa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112571/
https://www.ncbi.nlm.nih.gov/pubmed/27853267
http://dx.doi.org/10.1038/srep37094