Cinaciguat prevents the development of pathologic hypertrophy in a rat model of left ventricular pressure overload

Pathologic myocardial hypertrophy develops when the heart is chronically pressure-overloaded. Elevated intracellular cGMP-levels have been reported to prevent the development of pathologic myocardial hypertrophy, therefore we investigated the effects of chronic activation of the cGMP producing enzym...

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Detalles Bibliográficos
Autores principales: Németh, Balázs Tamás, Mátyás, Csaba, Oláh, Attila, Lux, Árpád, Hidi, László, Ruppert, Mihály, Kellermayer, Dalma, Kökény, Gábor, Szabó, Gábor, Merkely, Béla, Radovits, Tamás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112572/
https://www.ncbi.nlm.nih.gov/pubmed/27853261
http://dx.doi.org/10.1038/srep37166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112572/
https://www.ncbi.nlm.nih.gov/pubmed/27853261
http://dx.doi.org/10.1038/srep37166

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