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Allele-specific antibodies to Plasmodium vivax merozoite surface protein-1: prevalence and inverse relationship to haemoglobin levels during infection

BACKGROUND: Antigenic polymorphisms are considered as one of the main strategies employed by malaria parasites to escape from the host immune responses after infections. Merozoite surface protein-1 (MSP-1) of Plasmodium vivax, a promising vaccine candidate, is a highly polymorphic protein whose immu...

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Detalles Bibliográficos
Autores principales: Sepúlveda, Nuno, Morais, Cristiane Guimarães, Mourão, Luiza Carvalho, Freire, Matheus França, Fontes, Cor Jesus F., Lacerda, Marcus Vinícius G., Drakeley, Chris J., Braga, Érika Martins
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112628/
https://www.ncbi.nlm.nih.gov/pubmed/27852258
http://dx.doi.org/10.1186/s12936-016-1612-z