Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II

BACKGROUND: Lapachol is a natural naphthoquinone compound that possesses extensive biological activities. The aim of this study is to investigate the inhibitory effects of lapachol on rat C6 glioma both in vitro and in vivo, as well as the potential mechanisms. METHODS: The antitumor effect of lapac...

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Detalles Bibliográficos
Autores principales: Xu, Huanli, Chen, Qunying, Wang, Hong, Xu, Pingxiang, Yuan, Ru, Li, Xiaorong, Bai, Lu, Xue, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112657/
https://www.ncbi.nlm.nih.gov/pubmed/27852319
http://dx.doi.org/10.1186/s13046-016-0455-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112657/
https://www.ncbi.nlm.nih.gov/pubmed/27852319
http://dx.doi.org/10.1186/s13046-016-0455-3

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