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A functional endosomal pathway is necessary for lysosome biogenesis in Drosophila

BACKGROUND: Lysosomes are the major catabolic compartment within eukaryotic cells, and their biogenesis requires the integration of the biosynthetic and endosomal pathways. Endocytosis and autophagy are the primary inputs of the lysosomal degradation pathway. Endocytosis is specifically needed for t...

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Detalles Bibliográficos
Autores principales: Jacomin, Anne-Claire, Fauvarque, Marie-Odile, Taillebourg, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112658/
https://www.ncbi.nlm.nih.gov/pubmed/27852225
http://dx.doi.org/10.1186/s12860-016-0115-7