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ADA3 regulates normal and tumor mammary epithelial cell proliferation through c-MYC

BACKGROUND: We have established the critical role of ADA3 as a coactivator of estrogen receptor (ER), as well as its role in cell cycle progression. Furthermore, we showed that ADA3 is predominantly nuclear in mammary epithelium, and in ER+, but is cytoplasmic in ER- breast cancers, the latter corre...

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Detalles Bibliográficos
Autores principales: Griffin, Nicolas I., Sharma, Gayatri, Zhao, Xiangshan, Mirza, Sameer, Srivastava, Shashank, Dave, Bhavana J., Aleskandarany, Mohammed, Rakha, Emad, Mohibi, Shakur, Band, Hamid, Band, Vimla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112670/
https://www.ncbi.nlm.nih.gov/pubmed/27852327
http://dx.doi.org/10.1186/s13058-016-0770-9