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Comprehensive screening of target molecules by next-generation sequencing in patients with malignant solid tumors: guiding entry into phase I clinical trials

It is still controversial whether comprehensive genome screening of target molecules by next generation sequencing (NGS) is needed to increase clinical efficacy of investigational drugs or accelerate drug development, although several studies are being carried out. Therefore, we performed a prospect...

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Detalles Bibliográficos
Autores principales: Tanabe, Yuko, Ichikawa, Hitoshi, Kohno, Takashi, Yoshida, Hiroshi, Kubo, Takashi, Kato, Mamoru, Iwasa, Satoru, Ochiai, Atsushi, Yamamoto, Noboru, Fujiwara, Yasuhiro, Tamura, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112718/
https://www.ncbi.nlm.nih.gov/pubmed/27852271
http://dx.doi.org/10.1186/s12943-016-0553-z