Cargando…

Comprehensive screening of target molecules by next-generation sequencing in patients with malignant solid tumors: guiding entry into phase I clinical trials

It is still controversial whether comprehensive genome screening of target molecules by next generation sequencing (NGS) is needed to increase clinical efficacy of investigational drugs or accelerate drug development, although several studies are being carried out. Therefore, we performed a prospect...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tanabe, Yuko, Ichikawa, Hitoshi, Kohno, Takashi, Yoshida, Hiroshi, Kubo, Takashi, Kato, Mamoru, Iwasa, Satoru, Ochiai, Atsushi, Yamamoto, Noboru, Fujiwara, Yasuhiro, Tamura, Kenji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Letter to the Editor
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112718/ https://www.ncbi.nlm.nih.gov/pubmed/27852271 http://dx.doi.org/10.1186/s12943-016-0553-z

Ejemplares similares

Feasibility and utility of a panel testing for 114 cancer‐associated genes in a clinical setting: A hospital‐based study
por: Sunami, Kuniko, et al.
Publicado: (2019)

A computational tool to detect DNA alterations tailored to formalin-fixed paraffin-embedded samples in cancer clinical sequencing
por: Kato, Mamoru, et al.
Publicado: (2018)

Evaluating Clinical Genome Sequence Analysis by Watson for Genomics
por: Itahashi, Kota, et al.
Publicado: (2018)

Clonal Hematopoiesis From Next Generation Sequencing of Plasma From a Patient With Lung Adenocarcinoma: A Case Report
por: Ito, Munehiro, et al.
Publicado: (2020)

Re-expression of REG family and DUOXs genes in CRC organoids by co-culturing with CAFs
por: Naruse, Mie, et al.
Publicado: (2021)

Author Correction: Re-expression of REG family and DUOXs genes in CRC organoids by co-culturing with CAFs
por: Naruse, Mie, et al.
Publicado: (2021)

Endometrial cancer arising after complete remission of uterine malignant lymphoma: A case report and mutation analysis
por: Kuno, Ikumi, et al.
Publicado: (2019)

First‐in‐human study of the cancer peptide vaccine TAS0313 in patients with advanced solid tumors
por: Kondo, Shunsuke, et al.
Publicado: (2021)

Phase I study of Nivolumab, an anti-PD-1 antibody, in patients with malignant solid tumors
por: Yamamoto, Noboru, et al.
Publicado: (2016)

Pathological features of triple‐negative breast cancers that showed progressive disease during neoadjuvant chemotherapy
por: Tanabe, Yuko, et al.
Publicado: (2017)

Do all patients in the phase I oncology trials need to be hospitalized? Domestic but outstanding issues for globalization of drug development in Japan
por: Shimomura, Akihiko, et al.
Publicado: (2017)

First‐in‐human study of ONO‐4578, an antagonist of prostaglandin E(2) receptor 4, alone and with nivolumab in solid tumors
por: Iwasa, Satoru, et al.
Publicado: (2022)

Phase 1 pharmacokinetic study of the oral pan-AKT inhibitor MK-2206 in Japanese patients with advanced solid tumors
por: Doi, Toshihiko, et al.
Publicado: (2015)

Frequent amplification of receptor tyrosine kinase genes in well-differentiated/ dedifferentiated liposarcoma
por: Asano, Naofumi, et al.
Publicado: (2017)

Dose‐finding study of the checkpoint kinase 1 inhibitor, prexasertib, in Japanese patients with advanced solid tumors
por: Iwasa, Satoru, et al.
Publicado: (2018)

Impact of ALK Inhibitors in Patients With ALK-Rearranged Nonlung Solid Tumors
por: Takeyasu, Yuki, et al.
Publicado: (2021)

Phase I study of the indoleamine 2,3-dioxygenase 1 inhibitor navoximod (GDC-0919) as monotherapy and in combination with the PD-L1 inhibitor atezolizumab in Japanese patients with advanced solid tumours
por: Ebata, Takahiro, et al.
Publicado: (2019)

Alteration in molecular properties during establishment and passaging of endometrial carcinoma patient-derived xenografts
por: Imai, Toshio, et al.
Publicado: (2023)

Next generation sequencing‐based gene panel tests for the management of solid tumors
por: Nagahashi, Masayuki, et al.
Publicado: (2018)

Clinical Utility of Circulating Tumor DNA in Advanced Rare Cancers
por: Okuma, Hitomi Sumiyoshi, et al.
Publicado: (2021)

The safety, tolerability and pharmacokinetics of niraparib in Japanese patients with solid tumours: results of a phase I dose-escalation study
por: Yonemori, Kan, et al.
Publicado: (2021)

Safety and tolerability of AZD5363 in Japanese patients with advanced solid tumors
por: Tamura, Kenji, et al.
Publicado: (2016)

Dose Escalation Data from the Phase 1 Study of the Liposomal Formulation of Eribulin (E7389-LF) in Japanese Patients with Advanced Solid Tumors
por: Sato, Jun, et al.
Publicado: (2022)

Anti-stress effects of simplified aroma hand massage
por: Komori, Teruhisa, et al.
Publicado: (2018)

A first-in-human, phase 1 study of the NEDD8 activating enzyme E1 inhibitor TAS4464 in patients with advanced solid tumors
por: Yamamoto, Noboru, et al.
Publicado: (2021)

Five-year follow-up of nivolumab treatment in Japanese patients with esophageal squamous-cell carcinoma (ATTRACTION-1/ONO-4538-07)
por: Satoh, Taroh, et al.
Publicado: (2021)

Safety, tolerability, pharmacokinetics, and antitumour activity of oleclumab in Japanese patients with advanced solid malignancies: a phase I, open-label study
por: Kondo, Shunsuke, et al.
Publicado: (2022)

First‐in‐human phase I study of E7090, a novel selective fibroblast growth factor receptor inhibitor, in patients with advanced solid tumors
por: Koyama, Takafumi, et al.
Publicado: (2020)

NC-6004 Phase I study in combination with gemcitabine for advanced solid tumors and population PK/PD analysis
por: Doi, Toshihiko, et al.
Publicado: (2017)

Phase I study for ridaforolimus, an oral mTOR inhibitor, in Japanese patients with advanced solid tumors
por: Seki, Yoshitaka, et al.
Publicado: (2011)

Phase I study of palbociclib, a cyclin‐dependent kinase 4/6 inhibitor, in Japanese patients
por: Tamura, Kenji, et al.
Publicado: (2016)

Feasibility of genomic profiling with next-generation sequencing using specimens obtained by image-guided percutaneous needle biopsy
por: Sone, Miyuki, et al.
Publicado: (2019)

Topological Analysis for Arteriovenous Malformations via Computed Tomography Angiography: Part 1: Mathematical Concepts
por: Hata, Yuki, et al.
Publicado: (2014)

Whole genome sequencing to identify predictive markers for the risk of drug-induced interstitial lung disease
por: Udagawa, Chihiro, et al.
Publicado: (2019)

The Japanese Society of Pathology Practical Guidelines on the handling of pathological tissue samples for cancer genomic medicine
por: Hatanaka, Yutaka, et al.
Publicado: (2021)

Oral formulation of bendamustine hydrochloride for patients with advanced solid tumors; a phase 1 study
por: Shimizu, Toshio, et al.
Publicado: (2022)

Mode of entry of a vaporized pyrethroid knockdown agent into the body of the housefly, Musca domestica (Diptera: Muscidae)
por: Sumita, Yusuke, et al.
Publicado: (2016)

Primary Yolk Sac Tumor of the Omentum: A Case Report and Literature Review
por: Harano, Kenichi, et al.
Publicado: (2012)

The first case of SMARCB1 (INI1) - deficient squamous cell carcinoma of the pleura: a case report
por: Yoshida, Kazushi, et al.
Publicado: (2018)

Circulating cell-free plasma tumour DNA shows a higher incidence of EGFR mutations in patients with extrathoracic disease progression
por: Seki, Yoshitaka, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_4625p5c9egu9pc0ah983a40qf4