Is ApoE ɛ 4 a good biomarker for amyloid pathology in late onset Alzheimer’s disease?

Amyloid plaques are pathological hallmarks of Alzheimer’s Disease (AD) and biomarkers such as cerebrospinal fluid (CSF) β-amyloid 1–42 (Aβ1-42) and amyloid positron emission tomographic (PET) imaging are important in diagnosing amyloid pathology in vivo. ɛ4 allele of the Apolipoprotein E gene (ApoE...

Descripción completa

Detalles Bibliográficos
Autores principales: Ba, Maowen, Kong, Min, Li, Xiaofeng, Ng, Kok Pin, Rosa-Neto, Pedro, Gauthier, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112745/
https://www.ncbi.nlm.nih.gov/pubmed/27891223
http://dx.doi.org/10.1186/s40035-016-0067-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112745/
https://www.ncbi.nlm.nih.gov/pubmed/27891223
http://dx.doi.org/10.1186/s40035-016-0067-z

Ejemplares similares