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Is ApoE ɛ 4 a good biomarker for amyloid pathology in late onset Alzheimer’s disease?

Amyloid plaques are pathological hallmarks of Alzheimer’s Disease (AD) and biomarkers such as cerebrospinal fluid (CSF) β-amyloid 1–42 (Aβ1-42) and amyloid positron emission tomographic (PET) imaging are important in diagnosing amyloid pathology in vivo. ɛ4 allele of the Apolipoprotein E gene (ApoE...

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Detalles Bibliográficos
Autores principales:	Ba, Maowen, Kong, Min, Li, Xiaofeng, Ng, Kok Pin, Rosa-Neto, Pedro, Gauthier, Serge
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112745/ https://www.ncbi.nlm.nih.gov/pubmed/27891223 http://dx.doi.org/10.1186/s40035-016-0067-z

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