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Unravelling the Genome-Wide Contributions of Specific 2-Alkyl-4-Quinolones and PqsE to Quorum Sensing in Pseudomonas aeruginosa

The pqs quorum sensing (QS) system is crucial for Pseudomonas aeruginosa virulence both in vitro and in animal models of infection and is considered an ideal target for the development of anti-virulence agents. However, the precise role played by each individual component of this complex QS circuit...

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Detalles Bibliográficos
Autores principales: Rampioni, Giordano, Falcone, Marilena, Heeb, Stephan, Frangipani, Emanuela, Fletcher, Matthew P., Dubern, Jean-Frédéric, Visca, Paolo, Leoni, Livia, Cámara, Miguel, Williams, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112799/
https://www.ncbi.nlm.nih.gov/pubmed/27851827
http://dx.doi.org/10.1371/journal.ppat.1006029