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Evaluation of a pharmacogenetic-based warfarin dosing algorithm in patients with low time in therapeutic range – study protocol for a randomized controlled trial

BACKGROUND: Time in therapeutic range (TTR) is a measurement of quality of warfarin therapy and lower TTR values (<50%) are associated with greater risk of thromboembolic and bleeding events. Recently, we developed a pharmacogenetic-based warfarin dosing algorithm specifically calibrated for a Br...

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Detalles Bibliográficos
Autores principales: Marcatto, Leiliane Rodrigues, Sacilotto, Luciana, Bueno, Carolina Tosin, Facin, Mirella, Strunz, Celia Maria Cassaro, Darrieux, Francisco Carlos Costa, Scanavacca, Maurício Ibrahim, Krieger, Jose Eduardo, Pereira, Alexandre Costa, Santos, Paulo Caleb Junior Lima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112885/
https://www.ncbi.nlm.nih.gov/pubmed/27855643
http://dx.doi.org/10.1186/s12872-016-0405-1