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Two-Step Production of Phenylpyruvic Acid from L-Phenylalanine by Growing and Resting Cells of Engineered Escherichia coli: Process Optimization and Kinetics Modeling

Phenylpyruvic acid (PPA) is widely used in the pharmaceutical, food, and chemical industries. Here, a two-step bioconversion process, involving growing and resting cells, was established to produce PPA from l-phenylalanine using the engineered Escherichia coli constructed previously. First, the biot...

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Detalles Bibliográficos
Autores principales: Hou, Ying, Hossain, Gazi Sakir, Li, Jianghua, Shin, Hyun-dong, Liu, Long, Du, Guocheng, Chen, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112894/
https://www.ncbi.nlm.nih.gov/pubmed/27851793
http://dx.doi.org/10.1371/journal.pone.0166457