RAS–Mitogen-Activated Protein Kinase Signal Is Required for Enhanced PD-L1 Expression in Human Lung Cancers

Ectopic programmed cell death ligand 1 (PD-L1) expression in non-small cell lung cancers (NSCLCs) is related to immune evasion by cancer, and it is a molecular target of immune checkpoint therapies. Although some altered signals in NSCLCs are responsible for ectopic PD-L1 expression, the precise mec...

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Detalles Bibliográficos
Autores principales: Sumimoto, Hidetoshi, Takano, Atsushi, Teramoto, Koji, Daigo, Yataro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112979/
https://www.ncbi.nlm.nih.gov/pubmed/27846317
http://dx.doi.org/10.1371/journal.pone.0166626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112979/
https://www.ncbi.nlm.nih.gov/pubmed/27846317
http://dx.doi.org/10.1371/journal.pone.0166626

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