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RAS–Mitogen-Activated Protein Kinase Signal Is Required for Enhanced PD-L1 Expression in Human Lung Cancers

Ectopic programmed cell death ligand 1 (PD-L1) expression in non-small cell lung cancers (NSCLCs) is related to immune evasion by cancer, and it is a molecular target of immune checkpoint therapies. Although some altered signals in NSCLCs are responsible for ectopic PD-L1 expression, the precise mec...

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Detalles Bibliográficos
Autores principales:	Sumimoto, Hidetoshi, Takano, Atsushi, Teramoto, Koji, Daigo, Yataro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112979/ https://www.ncbi.nlm.nih.gov/pubmed/27846317 http://dx.doi.org/10.1371/journal.pone.0166626

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