An Inhibitory Motif on the 5’UTR of Several Rotavirus Genome Segments Affects Protein Expression and Reverse Genetics Strategies

Rotavirus genome consists of eleven segments of dsRNA, each encoding one single protein. Viral mRNAs contain an open reading frame (ORF) flanked by relatively short untranslated regions (UTRs), whose role in the viral cycle remains elusive. Here we investigated the role of 5’UTRs in T7 polymerase-dr...

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Detalles Bibliográficos
Autores principales: De Lorenzo, Giuditta, Drikic, Marija, Papa, Guido, Eichwald, Catherine, Burrone, Oscar R., Arnoldi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112996/
https://www.ncbi.nlm.nih.gov/pubmed/27846320
http://dx.doi.org/10.1371/journal.pone.0166719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112996/
https://www.ncbi.nlm.nih.gov/pubmed/27846320
http://dx.doi.org/10.1371/journal.pone.0166719

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