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Kinetic Modeling of ABCG2 Transporter Heterogeneity: A Quantitative, Single-Cell Analysis of the Side Population Assay

The side population (SP) assay, a technique used in cancer and stem cell research, assesses the activity of ABC transporters on Hoechst staining in the presence and absence of transporter inhibition, identifying SP and non-SP cell (NSP) subpopulations by differential staining intensity. The interpre...

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Detalles Bibliográficos
Autores principales: Prasanphanich, Adam F., White, Douglas E., Gran, Margaret A., Kemp, Melissa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113006/
https://www.ncbi.nlm.nih.gov/pubmed/27851764
http://dx.doi.org/10.1371/journal.pcbi.1005188