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A multiscale computational model predicts distribution of anti-angiogenic isoform VEGF(165b) in peripheral arterial disease in human and mouse
Angiogenesis is the growth of new blood vessels from pre-existing microvessels. Peripheral arterial disease (PAD) is caused by atherosclerosis that results in ischemia mostly in the lower extremities. Clinical trials including VEGF-A administration for therapeutic angiogenesis have not been successf...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113071/ https://www.ncbi.nlm.nih.gov/pubmed/27853189 http://dx.doi.org/10.1038/srep37030 |