A multiscale computational model predicts distribution of anti-angiogenic isoform VEGF(165b) in peripheral arterial disease in human and mouse

Angiogenesis is the growth of new blood vessels from pre-existing microvessels. Peripheral arterial disease (PAD) is caused by atherosclerosis that results in ischemia mostly in the lower extremities. Clinical trials including VEGF-A administration for therapeutic angiogenesis have not been successf...

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Detalles Bibliográficos
Autores principales: Chu, Liang-Hui, Ganta, Vijay Chaitanya, Choi, Min H., Chen, George, Finley, Stacey D., Annex, Brian H., Popel, Aleksander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113071/
https://www.ncbi.nlm.nih.gov/pubmed/27853189
http://dx.doi.org/10.1038/srep37030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113071/
https://www.ncbi.nlm.nih.gov/pubmed/27853189
http://dx.doi.org/10.1038/srep37030

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