Mucosal vaccination with a live recombinant rhinovirus followed by intradermal DNA administration elicits potent and protective HIV-specific immune responses

Mucosal immunity is deemed crucial to control sexual transmission of human immunodeficiency virus (HIV). Herein we report the efficacy of a mucosal HIV vaccine strategy comprising intranasal (IN) vaccination with a cocktail of live recombinant human rhinoviruses (HRVs) encoding overlapping fragments...

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Detalles Bibliográficos
Autores principales: Tomusange, Khamis, Wijesundara, Danushka, Gummow, Jason, Wesselingh, Steve, Suhrbier, Andreas, Gowans, Eric J., Grubor-Bauk, Branka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113119/
https://www.ncbi.nlm.nih.gov/pubmed/27853256
http://dx.doi.org/10.1038/srep36658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113119/
https://www.ncbi.nlm.nih.gov/pubmed/27853256
http://dx.doi.org/10.1038/srep36658

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