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Unmasking the U2AF homology motif family: a bona fide protein–protein interaction motif in disguise
U2AF homology motifs (UHM) that recognize U2AF ligand motifs (ULM) are an emerging family of protein–protein interaction modules. UHM–ULM interactions recur in pre-mRNA splicing factors including U2AF1 and SF3b1, which are frequently mutated in myelodysplastic syndromes. The core topology of the UHM...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113200/ https://www.ncbi.nlm.nih.gov/pubmed/27852923 http://dx.doi.org/10.1261/rna.057950.116 |