Nonmutational compensation of the fitness cost of antibiotic resistance in mycobacteria by overexpression of tlyA rRNA methylase

Several studies over the last few decades have shown that antibiotic resistance mechanisms frequently confer a fitness cost and that these costs can be genetically ameliorated by intra- or extragenic second-site mutations, often without loss of resistance. Another, much less studied potential mechan...

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Detalles Bibliográficos
Autores principales: Freihofer, Pietro, Akbergenov, Rashid, Teo, Youjin, Juskeviciene, Reda, Andersson, Dan I., Böttger, Erik C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113204/
https://www.ncbi.nlm.nih.gov/pubmed/27698071
http://dx.doi.org/10.1261/rna.057257.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113204/
https://www.ncbi.nlm.nih.gov/pubmed/27698071
http://dx.doi.org/10.1261/rna.057257.116

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