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Solution structure of the 5′-terminal hairpin of the 7SK small nuclear RNA

The small nuclear 7SK RNA regulates RNA polymerase II (RNA Pol II) transcription, by sequestering and inhibiting the positive transcription elongation factor b (P-TEFb). P-TEFb is stored in the 7SK ribonucleoprotein (RNP) that contains the three nuclear proteins Hexim1, LaRP7, and MePCE. P-TEFb inte...

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Detalles Bibliográficos
Autores principales: Bourbigot, Sarah, Dock-Bregeon, Anne-Catherine, Eberling, Pascal, Coutant, Jérôme, Kieffer, Bruno, Lebars, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113205/
https://www.ncbi.nlm.nih.gov/pubmed/27852926
http://dx.doi.org/10.1261/rna.056523.116