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Solution structure of the 5′-terminal hairpin of the 7SK small nuclear RNA
The small nuclear 7SK RNA regulates RNA polymerase II (RNA Pol II) transcription, by sequestering and inhibiting the positive transcription elongation factor b (P-TEFb). P-TEFb is stored in the 7SK ribonucleoprotein (RNP) that contains the three nuclear proteins Hexim1, LaRP7, and MePCE. P-TEFb inte...
Autores principales: | Bourbigot, Sarah, Dock-Bregeon, Anne-Catherine, Eberling, Pascal, Coutant, Jérôme, Kieffer, Bruno, Lebars, Isabelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113205/ https://www.ncbi.nlm.nih.gov/pubmed/27852926 http://dx.doi.org/10.1261/rna.056523.116 |
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