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Fluorophore ligand binding and complex stabilization of the RNA Mango and RNA Spinach aptamers
The effective tracking and purification of biological RNAs and RNA protein complexes is currently challenging. One promising strategy to simultaneously address both of these problems is to develop high-affinity RNA aptamers against taggable small molecule fluorophores. RNA Mango is a 39-nucleotide,...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113208/ https://www.ncbi.nlm.nih.gov/pubmed/27777365 http://dx.doi.org/10.1261/rna.056226.116 |