Cargando…

Fluorophore ligand binding and complex stabilization of the RNA Mango and RNA Spinach aptamers

The effective tracking and purification of biological RNAs and RNA protein complexes is currently challenging. One promising strategy to simultaneously address both of these problems is to develop high-affinity RNA aptamers against taggable small molecule fluorophores. RNA Mango is a 39-nucleotide,...

Descripción completa

Detalles Bibliográficos
Autores principales: Jeng, Sunny C.Y., Chan, Hedy H.Y., Booy, Evan P., McKenna, Sean A., Unrau, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113208/
https://www.ncbi.nlm.nih.gov/pubmed/27777365
http://dx.doi.org/10.1261/rna.056226.116