In vitro prion-like behaviour of TDP-43 in ALS

Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease (MND), and > 95% of familial and sporadic cases involve the deposition of insoluble aggregated, phosphorylated and cleaved TDP-43 protein. Accumulating clinical and biological evidence now indicates that ALS bears...

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Detalles Bibliográficos
Autores principales: Smethurst, Phillip, Newcombe, Jia, Troakes, Claire, Simone, Roberto, Chen, Yun-Ru, Patani, Rickie, Sidle, Katie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113659/
https://www.ncbi.nlm.nih.gov/pubmed/27590623
http://dx.doi.org/10.1016/j.nbd.2016.08.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113659/
https://www.ncbi.nlm.nih.gov/pubmed/27590623
http://dx.doi.org/10.1016/j.nbd.2016.08.007

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