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PDGFRα signalling promotes fibrogenic responses in collagen‐producing cells in Duchenne muscular dystrophy

Fibrosis is a characteristic of Duchenne muscular dystrophy (DMD), yet the cellular and molecular mechanisms responsible for DMD fibrosis are poorly understood. Utilizing the Collagen1a1‐GFP transgene to identify cells producing Collagen‐I matrix in wild‐type mice exposed to toxic injury or those mu...

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Detalles Bibliográficos
Autores principales: Ieronimakis, Nicholas, Hays, Aislinn, Prasad, Amalthiya, Janebodin, Kajohnkiart, Duffield, Jeremy S, Reyes, Morayma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113675/
https://www.ncbi.nlm.nih.gov/pubmed/27569721
http://dx.doi.org/10.1002/path.4801