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Supramolecular Control over Split‐Luciferase Complementation

Supramolecular split‐enzyme complementation restores enzymatic activity and allows for on–off switching. Split‐luciferase fragment pairs were provided with an N‐terminal FGG sequence and screened for complementation through host‐guest binding to cucurbit[8]uril (Q8). Split‐luciferase heterocomplex f...

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Detalles Bibliográficos
Autores principales: Bosmans, Ralph P. G., Briels, Jeroen M., Milroy, Lech‐Gustav, de Greef, Tom F. A., Merkx, Maarten, Brunsveld, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113697/
https://www.ncbi.nlm.nih.gov/pubmed/27356091
http://dx.doi.org/10.1002/anie.201602807