Extended‐Release Once‐Daily Formulation of Tofacitinib: Evaluation of Pharmacokinetics Compared With Immediate‐Release Tofacitinib and Impact of Food

Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis. An extended‐release (XR) formulation has been designed to provide a once‐daily (QD) dosing option to patients to achieve comparable pharmacokinetic (PK) parameters to the twice‐daily immediate‐release (IR) formu...

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Detalles Bibliográficos
Autores principales: Lamba, Manisha, Wang, Rong, Fletcher, Tracey, Alvey, Christine, Kushner, Joseph, Stock, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Drug‐Food Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113768/
https://www.ncbi.nlm.nih.gov/pubmed/26970526
http://dx.doi.org/10.1002/jcph.734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113768/
https://www.ncbi.nlm.nih.gov/pubmed/26970526
http://dx.doi.org/10.1002/jcph.734

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