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An Integrative Approach to Computational Modelling of the Gene Regulatory Network Controlling Clostridium botulinum Type A1 Toxin Production

Clostridium botulinum produces botulinum neurotoxins (BoNTs), highly potent substances responsible for botulism. Currently, mathematical models of C. botulinum growth and toxigenesis are largely aimed at risk assessment and do not include explicit genetic information beyond group level but integrate...

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Detalles Bibliográficos
Autores principales: Ihekwaba, Adaoha E. C., Mura, Ivan, Walshaw, John, Peck, Michael W., Barker, Gary C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113860/
https://www.ncbi.nlm.nih.gov/pubmed/27855161
http://dx.doi.org/10.1371/journal.pcbi.1005205