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An Integrative Approach to Computational Modelling of the Gene Regulatory Network Controlling Clostridium botulinum Type A1 Toxin Production
Clostridium botulinum produces botulinum neurotoxins (BoNTs), highly potent substances responsible for botulism. Currently, mathematical models of C. botulinum growth and toxigenesis are largely aimed at risk assessment and do not include explicit genetic information beyond group level but integrate...
Autores principales: | Ihekwaba, Adaoha E. C., Mura, Ivan, Walshaw, John, Peck, Michael W., Barker, Gary C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113860/ https://www.ncbi.nlm.nih.gov/pubmed/27855161 http://dx.doi.org/10.1371/journal.pcbi.1005205 |
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