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Role of p14(ARF) and p15(INK4B) promoter methylation in patients with lung cancer: a systematic meta-analysis

BACKGROUND: The cyclin-dependent kinase inhibitors p14(ARF) and p15(INK4B) are tumor suppressor genes that have been reported to be silenced through promoter methylation in many human cancers. However, the strength of association between p14(ARF) or p15(INK4B) promoter methylation and lung cancer re...

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Detalles Bibliográficos
Autores principales: Yang, Xinmei, Yang, Lei, Dai, Wanrong, Ye, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113922/
https://www.ncbi.nlm.nih.gov/pubmed/27956841
http://dx.doi.org/10.2147/OTT.S117161