A Single Dose-Escalation Study to Evaluate the Safety and Pharmacokinetics of Orally Administered Des-Aspartate Angiotensin I in Healthy Subjects

Des-aspartate-angiotensin I (DAA-I) is an endogenous angiotensin peptide and a prototype angiotensin receptor agonist (ARA). It acts on the angiotensin AT(1) receptor and antagonises the deleterious actions of angiotensin II. DAA-I attenuates animal models of human disease in which angiotensin II ha...

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Detalles Bibliográficos
Autores principales: Lee, Ko-Onn, Khoo, Chin-Meng, Chowbay, Balram, Chan, Yiong-Huak, Sim, Meng-Kwoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114201/
https://www.ncbi.nlm.nih.gov/pubmed/27681888
http://dx.doi.org/10.1007/s40268-016-0143-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114201/
https://www.ncbi.nlm.nih.gov/pubmed/27681888
http://dx.doi.org/10.1007/s40268-016-0143-y

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