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Overview on poly(ADP-ribose) immuno-biomedicine and future prospects
Poly(ADP-ribose), identified in 1966 independently by three groups Strassbourg, Kyoto and Tokyo, is synthesized by poly(ADP-ribose) polymerases (PARP) from NAD(+) as a substrate in the presence of Mg(2+). The structure was unique in that it has ribose-ribose linkage. In the early-1970s, however, its...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Japan Academy
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114291/ https://www.ncbi.nlm.nih.gov/pubmed/27477457 http://dx.doi.org/10.2183/pjab.92.222 |