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Microglial phospholipase D4 deficiency influences myelination during brain development

Phospholipase D4 (PLD4) is expressed in activated microglia that transiently appear in white matter during postnatal brain development. Previous knockdown experiments using cultured microglia showed PLD4 involvement in phagocytosis and proliferation. To elucidate the role of PLD4 in vivo, PLD4-defic...

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Detalles Bibliográficos
Autores principales: CHIBA, Terumasa, OTANI, Yoshinori, YAMAGUCHI, Yoshihide, ISHIBASHI, Tomoko, HAYASHI, Akiko, TANAKA, Kenji F., YAMAZAKI, Maya, SAKIMURA, Kenji, BABA, Hiroko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114292/
https://www.ncbi.nlm.nih.gov/pubmed/27477458
http://dx.doi.org/10.2183/pjab.92.237