The Role of Interaction Model in Simulation of Drug Interactions and QT Prolongation

Computational modelling is a cornerstone of Comprehensive In Vitro Proarrhythmia Assay and is re-increasingly being used in drug development. Electrophysiological effects of drug-drug interactions can be predicted in silico, e.g. with the use of in vitro cardiac ion channel data, PK profiles and hum...

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Detalles Bibliográficos
Autores principales: Wiśniowska, Barbara, Polak, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Pharmacometrics (H Kimko, Section Editor)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114317/
https://www.ncbi.nlm.nih.gov/pubmed/27917367
http://dx.doi.org/10.1007/s40495-016-0075-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114317/
https://www.ncbi.nlm.nih.gov/pubmed/27917367
http://dx.doi.org/10.1007/s40495-016-0075-9

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