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The Role of Interaction Model in Simulation of Drug Interactions and QT Prolongation
Computational modelling is a cornerstone of Comprehensive In Vitro Proarrhythmia Assay and is re-increasingly being used in drug development. Electrophysiological effects of drug-drug interactions can be predicted in silico, e.g. with the use of in vitro cardiac ion channel data, PK profiles and hum...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114317/ https://www.ncbi.nlm.nih.gov/pubmed/27917367 http://dx.doi.org/10.1007/s40495-016-0075-9 |