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Akkermansia muciniphila mediates negative effects of IFNγ on glucose metabolism

Cross-talk between the gut microbiota and the host immune system regulates host metabolism, and its dysregulation can cause metabolic disease. Here, we show that the gut microbe Akkermansia muciniphila can mediate negative effects of IFNγ on glucose tolerance. In IFNγ-deficient mice, A. muciniphila...

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Detalles Bibliográficos
Autores principales: Greer, Renee L., Dong, Xiaoxi, Moraes, Ana Carolina F., Zielke, Ryszard A., Fernandes, Gabriel R., Peremyslova, Ekaterina, Vasquez-Perez, Stephany, Schoenborn, Alexi A., Gomes, Everton P., Pereira, Alexandre C., Ferreira, Sandra R. G., Yao, Michael, Fuss, Ivan J., Strober, Warren, Sikora, Aleksandra E., Taylor, Gregory A., Gulati, Ajay S., Morgun, Andrey, Shulzhenko, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114536/
https://www.ncbi.nlm.nih.gov/pubmed/27841267
http://dx.doi.org/10.1038/ncomms13329